| Reaction Details |
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 | Report a problem with these data |
| Target | Large T antigen |
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| Ligand | BDBM59059 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits |
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| EC50 | >50000±n/a nM |
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| Citation |  PubChem, PC Identification of SV40 T antigen inhibitors: Cytotoxicity screen of selected hits PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Large T antigen |
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| Name: | Large T antigen |
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| Synonyms: | LT | LT-AG | LT_SV40 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 81575.54 |
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| Organism: | Simian virus 40 |
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| Description: | P03070 |
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| Residue: | 708 |
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| Sequence: | MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK
KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS
QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP
FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE
MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM
LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR
YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQAR
FVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK
ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE
TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
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| BDBM59059 |
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| n/a |
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| Name | BDBM59059 |
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| Synonyms: | 4-amyl-1-thioxo-2H-[1,2,4]triazolo[4,3-a]quinazolin-5-one | 4-pentyl-1-sulfanylidene-2H-[1,2,4]triazolo[4,3-a]quinazolin-5-one | MLS001171361 | SMR000588310 | US20230365568, Compound 24 | cid_2081016 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H16N4OS |
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| Mol. Mass. | 288.368 |
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| SMILES | CCCCCn1c2n[nH]c(=S)n2c2ccccc2c1=O |
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| Structure | 
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