| Reaction Details |
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 | Report a problem with these data |
| Target | Nucleotide-binding oligomerization domain-containing protein 1 |
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| Ligand | BDBM37726 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS luminescence assay for the identification of compounds that inhibit NOD1 |
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| EC50 | 14300±n/a nM |
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| Citation |  PubChem, PC uHTS luminescence assay for the identification of compounds that inhibit NOD1 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Nucleotide-binding oligomerization domain-containing protein 1 |
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| Name: | Nucleotide-binding oligomerization domain-containing protein 1 |
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| Synonyms: | CARD4 | NOD1 | NOD1_HUMAN | nucleotide-binding oligomerization domain containing 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 107699.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_5174617 |
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| Residue: | 953 |
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| Sequence: | MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCA
CPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVV
VNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSL
ACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFS
CFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPD
SSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAY
ARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMT
LTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQ
EEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQEL
LRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAK
QKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIY
ETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGV
RELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKIL
DECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHP
SLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKH
LWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF
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| BDBM37726 |
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| n/a |
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| Name | BDBM37726 |
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| Synonyms: | 1-[2-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-4-methyl-1,3-thiazol-5-yl]ethanone | 1-[2-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-4-methyl-5-thiazolyl]ethanone | 1-[2-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-4-methyl-thiazol-5-yl]ethanone | 1-{2-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-4-methyl-1,3-thiazol-5-yl}ethanone | MLS000045468 | SMR000027225 | cid_3241407 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13N3O2S2 |
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| Mol. Mass. | 319.402 |
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| SMILES | COc1ccc2nc(Nc3nc(C)c(s3)C(C)=O)sc2c1 |
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| Structure | 
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