| Reaction Details |
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 | Report a problem with these data |
| Target | M17 leucyl aminopeptidase |
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| Ligand | BDBM31057 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) |
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| IC50 | 39180±n/a nM |
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| Citation |  PubChem, PC Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| M17 leucyl aminopeptidase |
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| Name: | M17 leucyl aminopeptidase |
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| Synonyms: | leucine aminopeptidase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 67834.32 |
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| Organism: | Plasmodium falciparum 3D7 |
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| Description: | gi_124809582 |
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| Residue: | 605 |
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| Sequence: | MYFSSLCKFLPISEKEKIYLNIVKKRFCKSNIYYNNNNNNIINYNKRGLKFYPFCNNLKK
NINFVNINNKKGINFHSINKERKMASEVPQVVSLDPTSIPIEYNTPIHDIKVQVYDIKGG
CNVEEGLTIFLVNNPGKENGPVKISSKVNDKNVSEFLKDENMEKFNVKLGTSKHFYMFND
NKNSVAVGYVGCGSVADLSEADMKRVVLSLVTMLHDNKLSKLTVVFEINVDKNLFRFFLE
TLFYEYMTDERFKSTDKNVNMEYIKHLGVYINNADTYKEEVEKARVYYFGTYYASQLIAA
PSNYCNPVSLSNAAVELAQKLNLEYKILGVKELEELKMGAYLSVGKGSMYPNKFIHLTYK
SKGDVKKKIALVGKGITFDSGGYNLKAAPGSMIDLMKFDMSGCAAVLGCAYCVGTLKPEN
VEIHFLSAVCENMVSKNSYRPGDIITASNGKTIEVGNTDAEGRLTLADALVYAEKLGVDY
IVDIATLTGAMLYSLGTSYAGVFGNNEELINKILNSSKTSNEPVWWLPIINEYRATLNSK
YADINNISSSVKASSIVASLFLKEFVQNTAWAHIDIAGVSWNFKARKPKGFGVRLLTEFV
LNDAL
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|
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| BDBM31057 |
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| n/a |
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| Name | BDBM31057 |
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| Synonyms: | (4E)-2-hydroxy-4-[3-(2-methoxyphenyl)-5H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-6-ylidene]-1-cyclohexa-2,5-dienone | (4E)-2-hydroxy-4-[3-(2-methoxyphenyl)-5H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-6-ylidene]cyclohexa-2,5-dien-1-one | (4E)-4-[3-(2-methoxyphenyl)-5H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-6-ylidene]-2-oxidanyl-cyclohexa-2,5-dien-1-one | MLS000081447 | SMR000043338 | cid_5389565 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N4O3S |
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| Mol. Mass. | 354.383 |
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| SMILES | COc1ccccc1-c1nnc2SCC(=Nn12)c1ccc(O)c(O)c1 |c:15| |
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| Structure | 
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