| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM51770 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS absorbance assay for the identification of compounds that inhibit VHR1. |
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| IC50 | 1230±n/a nM |
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| Citation |  PubChem, PC uHTS absorbance assay for the identification of compounds that inhibit VHR1. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
|
|
|
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| BDBM51770 |
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| n/a |
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| Name | BDBM51770 |
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| Synonyms: | (4-amino-3-methyl-5-thieno[2,3-c]isothiazolyl)-(4-fluorophenyl)methanone | (4-amino-3-methyl-thien[2,3-c]isothiazol-5-yl)-(4-fluorophenyl)methanone | (4-amino-3-methylthieno[2,3-c][1,2]thiazol-5-yl)-(4-fluorophenyl)methanone | (4-amino-3-methylthieno[2,3-c]isothiazol-5-yl)(4-fluorophenyl)methanone | (4-azanyl-3-methyl-thieno[2,3-c][1,2]thiazol-5-yl)-(4-fluorophenyl)methanone | MLS000540418 | SMR000125676 | cid_1484492 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H9FN2OS2 |
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| Mol. Mass. | 292.352 |
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| SMILES | Cc1snc2sc(C(=O)c3ccc(F)cc3)c(N)c12 |
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| Structure | 
|
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