| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM48806 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS absorbance assay for the identification of compounds that inhibit VHR1. |
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| IC50 | 4680±n/a nM |
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| Citation |  PubChem, PC uHTS absorbance assay for the identification of compounds that inhibit VHR1. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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|
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| BDBM48806 |
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| n/a |
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| Name | BDBM48806 |
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| Synonyms: | (5Z)-3-(4-chlorobenzyl)-5-(4-hydroxy-3-methoxy-5-nitro-benzylidene)thiazolidine-2,4-quinone | (5Z)-3-[(4-chlorophenyl)methyl]-5-[(3-methoxy-5-nitro-4-oxidanyl-phenyl)methylidene]-1,3-thiazolidine-2,4-dione | (5Z)-3-[(4-chlorophenyl)methyl]-5-[(4-hydroxy-3-methoxy-5-nitrophenyl)methylidene]-1,3-thiazolidine-2,4-dione | (5Z)-3-[(4-chlorophenyl)methyl]-5-[(4-hydroxy-3-methoxy-5-nitrophenyl)methylidene]thiazolidine-2,4-dione | 3-(4-chlorobenzyl)-5-{4-hydroxy-3-nitro-5-methoxybenzylidene}-1,3-thiazolidine-2,4-dione | MLS000704847 | SMR000231699 | cid_1231306 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H13ClN2O6S |
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| Mol. Mass. | 420.824 |
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| SMILES | COc1cc(\C=C2/SC(=O)N(Cc3ccc(Cl)cc3)C2=O)cc(c1O)[N+]([O-])=O |
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| Structure | 
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