| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM51774 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS absorbance assay for the identification of compounds that inhibit VHR1. |
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| IC50 | 1860±n/a nM |
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| Citation |  PubChem, PC uHTS absorbance assay for the identification of compounds that inhibit VHR1. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
|
|
|
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| BDBM51774 |
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| n/a |
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| Name | BDBM51774 |
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| Synonyms: | 1'-({[4-(aminosulfonyl)phenyl]amino}carbonothioyl)-1,4'-bipiperidine-4'-carboxamide | 4-(1-piperidinyl)-1-[(4-sulfamoylanilino)-sulfanylidenemethyl]-4-piperidinecarboxamide | 4-piperidin-1-yl-1-[(4-sulfamoylphenyl)carbamothioyl]piperidine-4-carboxamide | 4-piperidino-1-[(4-sulfamoylphenyl)thiocarbamoyl]isonipecotamide | MLS000621463 | SMR000299565 | cid_2193503 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H27N5O3S2 |
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| Mol. Mass. | 425.569 |
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| SMILES | NC(=O)C1(CCN(CC1)C(=S)Nc1ccc(cc1)S(N)(=O)=O)N1CCCCC1 |
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| Structure | 
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