Ki Summary

Reaction Details

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Target

Dual specificity protein phosphatase 3

Ligand

BDBM51778

Substrate/Competitor

n/a

Meas. Tech.

uHTS absorbance assay for the identification of compounds that inhibit VHR1.

IC50

5100±n/a nM

Citation

PubChem, PC uHTS absorbance assay for the identification of compounds that inhibit VHR1. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Dual specificity protein phosphatase 3

Name:

Dual specificity protein phosphatase 3

Synonyms:

Type:

Hydrolase

Mol. Mass.:

20480.58

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

185

Sequence:

MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP

BDBM51778

n/a

Name

BDBM51778

Synonyms:

4-(4,5,6,7-tetrachloro-1,3-diketo-isoindolin-2-yl)cyclohexanecarboxylic acid | 4-(4,5,6,7-tetrachloro-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)cyclohexanecarboxylic acid | 4-(4,5,6,7-tetrachloro-1,3-dioxo-2-isoindolyl)-1-cyclohexanecarboxylic acid | 4-(4,5,6,7-tetrachloro-1,3-dioxoisoindol-2-yl)cyclohexane-1-carboxylic acid | 4-[4,5,6,7-tetrakis(chloranyl)-1,3-bis(oxidanylidene)isoindol-2-yl]cyclohexane-1-carboxylic acid | MLS001163330 | SMR000497238 | cid_1321147

Type

Small organic molecule

Emp. Form.

C15H11Cl4NO4

Mol. Mass.

411.064

SMILES

OC(=O)C1CCC(CC1)N1C(=O)c2c(C1=O)c(Cl)c(Cl)c(Cl)c2Cl |(16.37,-1.33,;15.6,,;16.37,1.33,;14.06,,;13.29,-1.33,;11.75,-1.33,;10.98,,;11.75,1.33,;13.29,1.33,;9.44,,;8.54,1.24,;9.02,2.7,;7.08,.77,;7.08,-.77,;8.54,-1.24,;9.02,-2.7,;5.75,-1.54,;5.75,-3.08,;4.41,-.77,;3.08,-1.54,;4.41,.77,;3.08,1.54,;5.75,1.54,;5.75,3.08,)|

Structure