| Reaction Details |
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 | Report a problem with these data |
| Target | Large T antigen |
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| Ligand | BDBM60399 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents |
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| IC50 | 4140±n/a nM |
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| Citation |  PubChem, PC Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Large T antigen |
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| Name: | Large T antigen |
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| Synonyms: | LT | LT-AG | LT_SV40 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 81575.54 |
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| Organism: | Simian virus 40 |
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| Description: | P03070 |
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| Residue: | 708 |
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| Sequence: | MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK
KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS
QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP
FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE
MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM
LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR
YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQAR
FVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK
ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE
TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
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| BDBM60399 |
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| n/a |
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| Name | BDBM60399 |
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| Synonyms: | 4-[3-(2,3-dihydro-1,4-benzodioxin-6-ylimino)-1,7-dihydroimidazo[1,2-a]pyrazin-2-ylidene]-1-cyclohexa-2,5-dienone | 4-[3-(2,3-dihydro-1,4-benzodioxin-6-ylimino)-1,7-dihydroimidazo[1,2-a]pyrazin-2-ylidene]cyclohexa-2,5-dien-1-one | MLS000116162 | SMR000093143 | cid_6324571 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16N4O3 |
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| Mol. Mass. | 360.366 |
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| SMILES | Oc1ccc(cc1)-c1nc2c[nH]ccn2c1=Nc1ccc2OCCOc2c1 |w:16.19| |
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| Structure | 
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