| Reaction Details |
|---|
 | Report a problem with these data |
| Target | SUMO-activating enzyme subunit 1 |
|---|
| Ligand | BDBM35371 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | uHTS HTRF assay for identification of inhibitors of SUMOylation |
|---|
| IC50 | 5600±n/a nM |
|---|
| Citation |  PubChem, PC uHTS HTRF assay for identification of inhibitors of SUMOylation PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| SUMO-activating enzyme subunit 1 |
|---|
| Name: | SUMO-activating enzyme subunit 1 |
|---|
| Synonyms: | AOS1 | SAE1 | SAE1_HUMAN | SUA1 | SUMO-activating enzyme subunit 1 (SAE1) | SUMO1 activating enzyme subunit 1 | UBLE1A |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 38440.84 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_17390638 |
|---|
| Residue: | 346 |
|---|
| Sequence: | MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA
PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
|
|
|
|---|
| BDBM35371 |
|---|
| n/a |
|---|
| Name | BDBM35371 |
|---|
| Synonyms: | (7-chloro-5-pyrrolidino-benzofurazan-4-yl)amine | 7-chloranyl-5-pyrrolidin-1-yl-2,1,3-benzoxadiazol-4-amine | 7-chloro-5-(1-pyrrolidinyl)-2,1,3-benzoxadiazol-4-amine | 7-chloro-5-pyrrolidin-1-yl-2,1,3-benzoxadiazol-4-amine | MLS000042514 | SMR000048561 | cid_667215 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H11ClN4O |
|---|
| Mol. Mass. | 238.674 |
|---|
| SMILES | Nc1c(cc(Cl)c2nonc12)N1CCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
