| Reaction Details |
|---|
 | Report a problem with these data |
| Target | SUMO-activating enzyme subunit 1 |
|---|
| Ligand | BDBM61236 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | uHTS HTRF assay for identification of inhibitors of SUMOylation |
|---|
| IC50 | 8710±n/a nM |
|---|
| Citation |  PubChem, PC uHTS HTRF assay for identification of inhibitors of SUMOylation PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| SUMO-activating enzyme subunit 1 |
|---|
| Name: | SUMO-activating enzyme subunit 1 |
|---|
| Synonyms: | AOS1 | SAE1 | SAE1_HUMAN | SUA1 | SUMO-activating enzyme subunit 1 (SAE1) | SUMO1 activating enzyme subunit 1 | UBLE1A |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 38440.84 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_17390638 |
|---|
| Residue: | 346 |
|---|
| Sequence: | MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA
PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
|
|
|
|---|
| BDBM61236 |
|---|
| n/a |
|---|
| Name | BDBM61236 |
|---|
| Synonyms: | 2-{4-[(2-Hydroxy-benzoyl)-hydrazonomethyl]-2-methoxy-phenoxy}-N-phenyl-acetamide | MLS001212428 | N-[[3-methoxy-4-(2-oxidanylidene-2-phenylazanyl-ethoxy)phenyl]methylideneamino]-2-oxidanyl-benzamide | N-[[4-(2-anilino-2-keto-ethoxy)-3-methoxy-benzylidene]amino]-2-hydroxy-benzamide | N-[[4-(2-anilino-2-oxoethoxy)-3-methoxyphenyl]methylideneamino]-2-hydroxybenzamide | SMR000515267 | cid_1105530 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H21N3O5 |
|---|
| Mol. Mass. | 419.4299 |
|---|
| SMILES | COc1cc(C=NNC(=O)c2ccccc2O)ccc1OCC(=O)Nc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
