| Reaction Details |
|---|
 | Report a problem with these data |
| Target | SUMO-activating enzyme subunit 1 |
|---|
| Ligand | BDBM61260 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | uHTS HTRF assay for identification of inhibitors of SUMOylation |
|---|
| IC50 | 6100±n/a nM |
|---|
| Citation |  PubChem, PC uHTS HTRF assay for identification of inhibitors of SUMOylation PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| SUMO-activating enzyme subunit 1 |
|---|
| Name: | SUMO-activating enzyme subunit 1 |
|---|
| Synonyms: | AOS1 | SAE1 | SAE1_HUMAN | SUA1 | SUMO-activating enzyme subunit 1 (SAE1) | SUMO1 activating enzyme subunit 1 | UBLE1A |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 38440.84 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_17390638 |
|---|
| Residue: | 346 |
|---|
| Sequence: | MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA
PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
|
|
|
|---|
| BDBM61260 |
|---|
| n/a |
|---|
| Name | BDBM61260 |
|---|
| Synonyms: | 3-(2,5-dioxo-1-pyrrolidinyl)-N-(4-methoxy-7-methyl-1,3-benzothiazol-2-yl)benzamide | 3-(2,5-dioxopyrrolidin-1-yl)-N-(4-methoxy-7-methyl-1,3-benzothiazol-2-yl)benzamide | 3-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]-N-(4-methoxy-7-methyl-1,3-benzothiazol-2-yl)benzamide | MLS001232856 | N-(4-methoxy-7-methyl-1,3-benzothiazol-2-yl)-3-succinimido-benzamide | SMR000806253 | cid_7172926 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H17N3O4S |
|---|
| Mol. Mass. | 395.432 |
|---|
| SMILES | COc1ccc(C)c2sc(NC(=O)c3cccc(c3)-n3c(O)ccc3O)nc12 |
|---|
| Structure | 
|
|---|
Search and Browse
