Reaction Details |
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Target | Eukaryotic translation initiation factor 4H |
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Ligand | BDBM50578 |
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Substrate/Competitor | n/a |
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Meas. Tech. | uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) |
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IC50 | 23645±n/a nM |
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Citation | PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Eukaryotic translation initiation factor 4H |
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Name: | Eukaryotic translation initiation factor 4H |
Synonyms: | EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 27385.24 |
Organism: | Homo sapiens (Human) |
Description: | Q15056 |
Residue: | 248 |
Sequence: | MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
QDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPM
GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE
EVVQKEQE
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BDBM50578 |
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n/a |
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Name | BDBM50578 |
Synonyms: | 3-[6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-phenyl-pentanoic acid | 5-phenyl-3-(3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl)oxy-valeric acid | 5-phenyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypentanoic acid | 5-phenyl-3-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]pentanoic acid | MLS000877001 | SMR000440688 | cid_16681750 |
Type | Small organic molecule |
Emp. Form. | C17H24O8 |
Mol. Mass. | 356.3677 |
SMILES | OCC1OC(OC(CCc2ccccc2)CC(O)=O)C(O)C(O)C1O |
Structure |
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