| Reaction Details |
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 | Report a problem with these data |
| Target | Eukaryotic translation initiation factor 4H |
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| Ligand | BDBM61325 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) |
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| IC50 | 7710±n/a nM |
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| Citation |  PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Eukaryotic translation initiation factor 4H |
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| Name: | Eukaryotic translation initiation factor 4H |
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| Synonyms: | EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 27385.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15056 |
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| Residue: | 248 |
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| Sequence: | MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
QDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPM
GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE
EVVQKEQE
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| BDBM61325 |
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| n/a |
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| Name | BDBM61325 |
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| Synonyms: | 1-N,3-N-bis(2-hydroxy-5-nitrophenyl)benzene-1,3-dicarboxamide | MLS001008494 | N,N'-bis(2-hydroxy-5-nitrophenyl)isophthalamide | N,N'-bis(2-hydroxy-5-nitro-phenyl)isophthalamide | N1,N3-bis(2-hydroxy-5-nitrophenyl)benzene-1,3-dicarboxamide | N1,N3-bis(5-nitro-2-oxidanyl-phenyl)benzene-1,3-dicarboxamide | SMR000495849 | cid_3823676 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H14N4O8 |
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| Mol. Mass. | 438.3472 |
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| SMILES | Oc1ccc(cc1NC(=O)c1cccc(c1)C(=O)Nc1cc(ccc1O)[N+]([O-])=O)[N+]([O-])=O |
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| Structure | 
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