| Reaction Details |
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 | Report a problem with these data |
| Target | Eukaryotic translation initiation factor 4H |
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| Ligand | BDBM61339 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) |
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| IC50 | 100000±n/a nM |
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| Citation |  PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Eukaryotic translation initiation factor 4H |
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| Name: | Eukaryotic translation initiation factor 4H |
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| Synonyms: | EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 27385.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15056 |
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| Residue: | 248 |
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| Sequence: | MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
QDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPM
GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE
EVVQKEQE
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| BDBM61339 |
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| n/a |
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| Name | BDBM61339 |
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| Synonyms: | 2-[(2Z)-2-[(1-methyl-2-pyridin-1-iumyl)methylidene]-1,3-benzothiazol-3-yl]ethanol;iodide | 2-[(2Z)-2-[(1-methylpyridin-1-ium-2-yl)methylene]-1,3-benzothiazol-3-yl]ethanol;iodide | 2-[(2Z)-2-[(1-methylpyridin-1-ium-2-yl)methylidene]-1,3-benzothiazol-3-yl]ethanol;iodide | 2-[3-(2-Hydroxy-ethyl)-3H-benzothiazol-2-ylidenemethyl]-1-methyl-pyridinium | MLS001212885 | SMR000518478 | cid_24747025 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17N2OS |
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| Mol. Mass. | 285.383 |
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| SMILES | C[n+]1ccccc1\C=C1/Sc2ccccc2N1CCO |
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| Structure | 
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