Ki Summary

Reaction Details

Report a problem with these data

Target

G-protein coupled receptor 55

Ligand

BDBM57891

Substrate/Competitor

n/a

Meas. Tech.

Image-Based HTS for Selective Antagonists for GPR55

IC50

500±n/a nM

Citation

PubChem, PC Image-Based HTS for Selective Antagonists for GPR55 PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

G-protein coupled receptor 55

Name:

G-protein coupled receptor 55

Synonyms:

G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN

Type:

PROTEIN

Mol. Mass.:

36649.72

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1292265

Residue:

319

Sequence:

MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATS
IYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRF
LAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAK
VFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFL
PVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIR
AHRPSRVQLVLQDTTISRG

BDBM57891

n/a

Name

BDBM57891

Synonyms:

4-[3-[(3-chloro-4-methoxy-phenyl)carbamoyl]-7-keto-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylic acid tert-butyl ester | 4-[3-[(3-chloro-4-methoxyanilino)-oxomethyl]-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]-1-piperidinecarboxylic acid tert-butyl ester | MLS000674599 | SMR000314041 | cid_6619478 | tert-butyl 4-(3-{[(3-chloro-4-methoxyphenyl)amino]carbonyl}-7-hydroxypyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate | tert-butyl 4-[3-[(3-chloranyl-4-methoxy-phenyl)carbamoyl]-7-oxidanylidene-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate | tert-butyl 4-[3-[(3-chloro-4-methoxyphenyl)carbamoyl]-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate

Type

Small organic molecule

Emp. Form.

C24H28ClN5O5

Mol. Mass.

501.963

SMILES

COc1ccc(NC(=O)c2c[nH]n3c2nc(cc3=O)C2CCN(CC2)C(=O)OC(C)(C)C)cc1Cl

Structure