| Reaction Details |
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 | Report a problem with these data |
| Target | Polyadenylate-binding protein 1 |
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| Ligand | BDBM50578 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) |
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| IC50 | 69430±n/a nM |
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| Citation |  PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Polyadenylate-binding protein 1 |
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| Name: | Polyadenylate-binding protein 1 |
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| Synonyms: | PAB1 | PABP | PABP1 | PABP1_HUMAN | PABPC1 | PABPC2 | poly(A) binding protein, cytoplasmic 1 | polyadenylate-binding protein 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 70694.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_46367787 |
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| Residue: | 636 |
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| Sequence: | MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
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| BDBM50578 |
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| n/a |
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| Name | BDBM50578 |
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| Synonyms: | 3-[6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-phenyl-pentanoic acid | 5-phenyl-3-(3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl)oxy-valeric acid | 5-phenyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypentanoic acid | 5-phenyl-3-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]pentanoic acid | MLS000877001 | SMR000440688 | cid_16681750 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H24O8 |
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| Mol. Mass. | 356.3677 |
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| SMILES | OCC1OC(OC(CCc2ccccc2)CC(O)=O)C(O)C(O)C1O |
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| Structure | 
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