| Reaction Details |
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 | Report a problem with these data |
| Target | Polyadenylate-binding protein 1 |
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| Ligand | BDBM61317 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) |
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| IC50 | 4075±n/a nM |
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| Citation |  PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Polyadenylate-binding protein 1 |
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| Name: | Polyadenylate-binding protein 1 |
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| Synonyms: | PAB1 | PABP | PABP1 | PABP1_HUMAN | PABPC1 | PABPC2 | poly(A) binding protein, cytoplasmic 1 | polyadenylate-binding protein 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 70694.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_46367787 |
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| Residue: | 636 |
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| Sequence: | MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
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| BDBM61317 |
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| n/a |
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| Name | BDBM61317 |
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| Synonyms: | 3-[[anilino(oxo)methyl]-[(2,4,6-trimethyl-1-cyclohex-3-enyl)methyl]amino]propyl-trimethylammonium;iodide | MLS000333849 | SMR000440173 | Trimethyl-{3-[3-phenyl-1-(2,4,6-trimethyl-cyclohex-3-enylmethyl)-ureido]-propyl}-ammonium | cid_2859481 | trimethyl-[3-[phenylcarbamoyl-[(2,4,6-trimethylcyclohex-3-en-1-yl)methyl]amino]propyl]ammonium;iodide | trimethyl-[3-[phenylcarbamoyl-[(2,4,6-trimethylcyclohex-3-en-1-yl)methyl]amino]propyl]azanium;iodide |
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| Type | Small organic molecule |
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| Emp. Form. | C23H38N3O |
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| Mol. Mass. | 372.5668 |
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| SMILES | CC1CC(C)=CC(C)C1CN(CCC[N+](C)(C)C)C(=O)Nc1ccccc1 |c:4| |
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| Structure | 
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