| Reaction Details |
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 | Report a problem with these data |
| Target | Polyadenylate-binding protein 1 |
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| Ligand | BDBM61332 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) |
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| IC50 | 5630±n/a nM |
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| Citation |  PubChem, PC uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Polyadenylate-binding protein 1 |
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| Name: | Polyadenylate-binding protein 1 |
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| Synonyms: | PAB1 | PABP | PABP1 | PABP1_HUMAN | PABPC1 | PABPC2 | poly(A) binding protein, cytoplasmic 1 | polyadenylate-binding protein 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 70694.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_46367787 |
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| Residue: | 636 |
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| Sequence: | MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
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| BDBM61332 |
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| n/a |
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| Name | BDBM61332 |
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| Synonyms: | 4-(2-Methoxy-phenylcarbamoyl)-1-methyl-pyridinium | MLS001203676 | N-(2-methoxyphenyl)-1-methyl-4-pyridin-1-iumcarboxamide;iodide | N-(2-methoxyphenyl)-1-methyl-pyridin-1-ium-4-carboxamide;iodide | N-(2-methoxyphenyl)-1-methylpyridin-1-ium-4-carboxamide;iodide | SMR000505100 | cid_16240614 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H15N2O2 |
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| Mol. Mass. | 243.2806 |
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| SMILES | COc1ccccc1NC(=O)c1cc[n+](C)cc1 |
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| Structure | 
|
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