| Reaction Details |
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 | Report a problem with these data |
| Target | Procathepsin L |
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| Ligand | BDBM60057 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). |
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| IC50 | >59642±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Procathepsin L |
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| Name: | Procathepsin L |
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| Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
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| Type: | Enzyme |
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| Mol. Mass.: | 37557.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purchased from Calbiochem (San Diego, CA). |
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| Residue: | 333 |
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| Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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| BDBM60057 |
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| n/a |
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| Name | BDBM60057 |
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| Synonyms: | MLS000698754 | N-(1,2-dihydro-5-acenaphthylenyl)-2-[(4-hydroxy-6-oxo-1-phenyl-1,6-dihydro-2-pyrimidinyl)sulfanyl]acetamide | N-(1,2-dihydroacenaphthylen-5-yl)-2-(6-hydroxy-4-oxo-1-phenylpyrimidin-2-yl)sulfanylacetamide | N-(1,2-dihydroacenaphthylen-5-yl)-2-(6-oxidanyl-4-oxidanylidene-1-phenyl-pyrimidin-2-yl)sulfanyl-ethanamide | N-(1,2-dihydroacenaphthylen-5-yl)-2-[(6-hydroxy-4-oxo-1-phenyl-2-pyrimidinyl)thio]acetamide | N-acenaphthen-5-yl-2-[(6-hydroxy-4-keto-1-phenyl-pyrimidin-2-yl)thio]acetamide | SMR000226481 | cid_1208699 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H19N3O3S |
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| Mol. Mass. | 429.491 |
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| SMILES | Oc1cc(=O)n(c(SCC(=O)Nc2ccc3CCc4cccc2c34)n1)-c1ccccc1 |
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| Structure | 
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