| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM54779 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of small molecule agonists of the kappa opioid receptor via a luminescent beta-arrestin assay |
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| EC50 | 4050±n/a nM |
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| Citation |  PubChem, PC SAR analysis of small molecule agonists of the kappa opioid receptor via a luminescent beta-arrestin assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM54779 |
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| n/a |
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| Name | BDBM54779 |
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| Synonyms: | MLS000048990 | N-(1-{[(2,6-dimethylphenyl)amino]carbonyl}cyclopentyl)-N-(2-furylmethyl)-2-pyridinecarboxamide | N-[1-[(2,6-dimethylanilino)-oxomethyl]cyclopentyl]-N-(2-furanylmethyl)-2-pyridinecarboxamide | N-[1-[(2,6-dimethylphenyl)carbamoyl]cyclopentyl]-N-(2-furfuryl)picolinamide | N-[1-[(2,6-dimethylphenyl)carbamoyl]cyclopentyl]-N-(furan-2-ylmethyl)pyridine-2-carboxamide | SMR000074223 | cid_1297443 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27N3O3 |
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| Mol. Mass. | 417.5002 |
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| SMILES | Cc1cccc(C)c1NC(=O)C1(CCCC1)N(Cc1ccco1)C(=O)c1ccccn1 |
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| Structure | 
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