Ki Summary

Reaction Details

Report a problem with these data

Target

Regulator of G-protein signaling 4

Ligand

BDBM62220

Substrate/Competitor

n/a

Meas. Tech.

Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds

EC50

30000±n/a nM

Citation

PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 4

Name:

Regulator of G-protein signaling 4

Synonyms:

RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)

Type:

Enzyme

Mol. Mass.:

23263.51

Organism:

Homo sapiens (Human)

Description:

P49798

Residue:

205

Sequence:

MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWA
ESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFIS
VQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNP
SSCGAEKQKGAKSSADCASLVPQCA

BDBM62220

n/a

Name

BDBM62220

Synonyms:

2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)-1-piperazinyl]-2-oxoethyl]-7,8-dihydro-1,6-naphthyridin-5-one | 2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxidanylidene-ethyl]-7,8-dihydro-1,6-naphthyridin-5-one | 2,4-dimethyl-6-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxoethyl]-7,8-dihydro-1,6-naphthyridin-5-one | 6-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]-2,4-dimethyl-7,8-dihydro-1,6-naphthyridin-5-one | KUC103675N | cid_44473131

Type

Small organic molecule

Emp. Form.

C24H30N4O2

Mol. Mass.

406.5206

SMILES

CC1CN(CCN1c1cccc(C)c1)C(=O)CN1CCc2nc(C)cc(C)c2C1=O

Structure