Reaction Details |
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Target | Sphingosine 1-phosphate receptor 4 |
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Ligand | BDBM62224 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4) |
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IC50 | 88820±n/a nM |
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Citation | PubChem, PC Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4) PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Sphingosine 1-phosphate receptor 4 |
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Name: | Sphingosine 1-phosphate receptor 4 |
Synonyms: | EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 41647.39 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 384 |
Sequence: | MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
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BDBM62224 |
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n/a |
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Name | BDBM62224 |
Synonyms: | (4,5-dibromo-6-oxopyridazin-1-yl)methyl 2,6-difluorobenzoate | 2,6-difluorobenzoic acid (4,5-dibromo-6-keto-pyridazin-1-yl)methyl ester | 2,6-difluorobenzoic acid (4,5-dibromo-6-oxo-1-pyridazinyl)methyl ester | SR-01000671432 | SR-01000671432-2 | [4,5-bis(bromanyl)-6-oxidanylidene-pyridazin-1-yl]methyl 2,6-bis(fluoranyl)benzoate | cid_1474490 |
Type | Small organic molecule |
Emp. Form. | C12H6Br2F2N2O3 |
Mol. Mass. | 423.992 |
SMILES | Fc1cccc(F)c1C(=O)OCn1ncc(Br)c(Br)c1=O |
Structure |
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