| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 4 |
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| Ligand | BDBM54824 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4) |
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| IC50 | 6739±n/a nM |
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| Citation |  PubChem, PC Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sphingosine 1-phosphate receptor 4 |
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| Name: | Sphingosine 1-phosphate receptor 4 |
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| Synonyms: | EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41647.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 384 |
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| Sequence: | MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
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| BDBM54824 |
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| n/a |
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| Name | BDBM54824 |
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| Synonyms: | 2-(4,5-dichloro-6-keto-pyridazin-1-yl)-N-(5-methoxy-2-methyl-4-nitro-phenyl)acetamide | 2-(4,5-dichloro-6-oxo-1-pyridazinyl)-N-(5-methoxy-2-methyl-4-nitrophenyl)acetamide | 2-(4,5-dichloro-6-oxopyridazin-1-yl)-N-(5-methoxy-2-methyl-4-nitrophenyl)acetamide | 2-[4,5-bis(chloranyl)-6-oxidanylidene-pyridazin-1-yl]-N-(5-methoxy-2-methyl-4-nitro-phenyl)ethanamide | MLS001006533 | SMR000349514 | cid_4019447 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12Cl2N4O5 |
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| Mol. Mass. | 387.175 |
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| SMILES | COc1cc(NC(=O)Cn2ncc(Cl)c(Cl)c2=O)c(C)cc1[N+]([O-])=O |
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| Structure | 
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