Reaction Details |
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Target | Sphingosine 1-phosphate receptor 4 |
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Ligand | BDBM62393 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): Synthesized analogues |
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IC50 | 414±n/a nM |
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Citation | PubChem, PC Late stage fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 4 (S1P4): Synthesized analogues PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Sphingosine 1-phosphate receptor 4 |
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Name: | Sphingosine 1-phosphate receptor 4 |
Synonyms: | EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 41647.39 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 384 |
Sequence: | MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
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BDBM62393 |
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n/a |
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Name | BDBM62393 |
Synonyms: | 5-(2-ethoxy-5-methoxy-phenyl)-N-(2-ethyl-6-methyl-phenyl)-2-furamide | 5-(2-ethoxy-5-methoxy-phenyl)-N-(2-ethyl-6-methyl-phenyl)furan-2-carboxamide | 5-(2-ethoxy-5-methoxyphenyl)-N-(2-ethyl-6-methylphenyl)-2-furancarboxamide | 5-(2-ethoxy-5-methoxyphenyl)-N-(2-ethyl-6-methylphenyl)furan-2-carboxamide | SR-02000000237 | SR-02000000237-1 | cid_44607578 |
Type | Small organic molecule |
Emp. Form. | C23H25NO4 |
Mol. Mass. | 379.4489 |
SMILES | CCOc1ccc(OC)cc1-c1ccc(o1)C(=O)Nc1c(C)cccc1CC |
Structure |
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