Ki Summary

Reaction Details

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Target

Sphingosine 1-phosphate receptor 5

Ligand

BDBM62392

Substrate/Competitor

n/a

Meas. Tech.

Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 5 (S1P5)

IC50

>25000±n/a nM

Citation

PubChem, PC Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 5 (S1P5) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Sphingosine 1-phosphate receptor 5

Name:

Sphingosine 1-phosphate receptor 5

Synonyms:

EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8

Type:

G Protein-Coupled Receptor (GPCR)

Mol. Mass.:

41796.42

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

398

Sequence:

MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD

BDBM62392

n/a

Name

BDBM62392

Synonyms:

5-(2,5-dimethoxyphenyl)-N-(2-ethyl-6-methyl-phenyl)-2-furamide | 5-(2,5-dimethoxyphenyl)-N-(2-ethyl-6-methyl-phenyl)furan-2-carboxamide | 5-(2,5-dimethoxyphenyl)-N-(2-ethyl-6-methylphenyl)-2-furancarboxamide | 5-(2,5-dimethoxyphenyl)-N-(2-ethyl-6-methylphenyl)furan-2-carboxamide | SR-02000000236 | SR-02000000236-1 | cid_44607572

Type

Small organic molecule

Emp. Form.

C22H23NO4

Mol. Mass.

365.4223

SMILES

CCc1cccc(C)c1NC(=O)c1ccc(o1)-c1cc(OC)ccc1OC

Structure