Ki Summary

Reaction Details

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Target

Sphingosine 1-phosphate receptor 5

Ligand

BDBM62396

Substrate/Competitor

n/a

Meas. Tech.

Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 5 (S1P5)

IC50

>25000±n/a nM

Citation

PubChem, PC Late stage counterscreen assay for S1P4 antagonists: Fluorescence dose response cell-based screening assay for antagonists of the Sphingosine 1-Phosphate Receptor 5 (S1P5) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Sphingosine 1-phosphate receptor 5

Name:

Sphingosine 1-phosphate receptor 5

Synonyms:

EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8

Type:

G Protein-Coupled Receptor (GPCR)

Mol. Mass.:

41796.42

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

398

Sequence:

MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD

BDBM62396

n/a

Name

BDBM62396

Synonyms:

N-(2,6-dimethylphenyl)-5-(4-methyl-3-thienyl)-2-furamide | N-(2,6-dimethylphenyl)-5-(4-methyl-3-thiophenyl)-2-furancarboxamide | N-(2,6-dimethylphenyl)-5-(4-methylthiophen-3-yl)furan-2-carboxamide | SR-02000000240 | SR-02000000240-1 | cid_44607581

Type

Small organic molecule

Emp. Form.

C18H17NO2S

Mol. Mass.

311.398

SMILES

Cc1cscc1-c1ccc(o1)C(=O)Nc1c(C)cccc1C

Structure