| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM43416 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HTS Image-Based Screen for Antagonists of the DOR Receptor |
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| IC50 | 6480±n/a nM |
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| Citation |  PubChem, PC HTS Image-Based Screen for Antagonists of the DOR Receptor PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM43416 |
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| n/a |
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| Name | BDBM43416 |
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| Synonyms: | MLS000375336 | N-[1-(1-adamantyl)ethyl]-2-(4,5-dichloro-6-keto-pyridazin-1-yl)acetamide | N-[1-(1-adamantyl)ethyl]-2-(4,5-dichloro-6-oxo-1-pyridazinyl)acetamide | N-[1-(1-adamantyl)ethyl]-2-(4,5-dichloro-6-oxopyridazin-1-yl)acetamide | N-[1-(1-adamantyl)ethyl]-2-[4,5-bis(chloranyl)-6-oxidanylidene-pyridazin-1-yl]ethanamide | SMR000254589 | cid_4811966 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23Cl2N3O2 |
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| Mol. Mass. | 384.3 |
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| SMILES | [H]C12CC3([H])CC([H])(C1)CC(C2)(C3)C(C)NC(=O)Cn1ncc(Cl)c(Cl)c1=O |TLB:8:6:12:1.11.2,8:1:12:6.9.5,THB:5:6:11:3.12.2| |
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| Structure | 
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