Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM54829 |
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Substrate/Competitor | n/a |
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Meas. Tech. | HTS Image-Based Screen for Antagonists of the DOR Receptor |
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IC50 | 14666±n/a nM |
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Citation | PubChem, PC HTS Image-Based Screen for Antagonists of the DOR Receptor PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM54829 |
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n/a |
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Name | BDBM54829 |
Synonyms: | 2-(7-Chloro-4-nitro-benzo[1,2,5]oxadiazol-5-ylamino)-phenol | 6-[(7-chloranyl-4-nitro-1,3-dihydro-2,1,3-benzoxadiazol-5-yl)imino]cyclohexa-2,4-dien-1-one | 6-[(7-chloro-4-nitro-1,3-dihydro-2,1,3-benzoxadiazol-5-yl)imino]-1-cyclohexa-2,4-dienone | 6-[(7-chloro-4-nitro-1,3-dihydro-2,1,3-benzoxadiazol-5-yl)imino]cyclohexa-2,4-dien-1-one | 6-[(7-chloro-4-nitro-1,3-dihydrobenzofurazan-5-yl)imino]cyclohexa-2,4-dien-1-one | MLS001210732 | SMR000516448 | cid_5719581 |
Type | Small organic molecule |
Emp. Form. | C12H7ClN4O4 |
Mol. Mass. | 306.661 |
SMILES | [O-]c1ccccc1Nc1cc(Cl)c2[nH+]onc2c1[N+]([O-])=O |
Structure |
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