| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM62187 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay |
|---|
| IC50 | 32000±n/a nM |
|---|
| Citation |  PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40382.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
|---|
| Residue: | 372 |
|---|
| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM62187 |
|---|
| n/a |
|---|
| Name | BDBM62187 |
|---|
| Synonyms: | (phenylmethyl) N-[2,2,2-tris(chloranyl)-1-[(2,4-dimethylphenyl)carbamothioylamino]ethyl]carbamate | MLS-0425689.0001 | N-[2,2,2-trichloro-1-[(2,4-dimethylphenyl)thiocarbamoylamino]ethyl]carbamic acid benzyl ester | N-[2,2,2-trichloro-1-[[(2,4-dimethylanilino)-sulfanylidenemethyl]amino]ethyl]carbamic acid (phenylmethyl) ester | benzyl N-[2,2,2-trichloro-1-[(2,4-dimethylphenyl)carbamothioylamino]ethyl]carbamate | cid_3091259 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H20Cl3N3O2S |
|---|
| Mol. Mass. | 460.805 |
|---|
| SMILES | Cc1ccc(NC(=S)NC(NC(=O)OCc2ccccc2)C(Cl)(Cl)Cl)c(C)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
