| Reaction Details |
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 | Report a problem with these data |
| Target | Epstein-Barr nuclear antigen 1 |
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| Ligand | BDBM62459 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) |
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| IC50 | 5900±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Epstein-Barr nuclear antigen 1 |
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| Name: | Epstein-Barr nuclear antigen 1 |
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| Synonyms: | EBNA-1 protein | EBNA1 | EBNA1_EBVB9 | Epstein-Barr virus protease (EBV Pr) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 56444.81 |
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| Organism: | Human herpesvirus 4 |
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| Description: | gi_23893623 |
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| Residue: | 641 |
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| Sequence: | MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGS
GSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGG
AGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGG
AGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGA
GAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGA
GGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRER
ARGGSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGEADYFEYHQE
GGPDGEPDVPPGAIEQGPADDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFEN
IAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLP
FGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSF
DDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE
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| BDBM62459 |
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| n/a |
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| Name | BDBM62459 |
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| Synonyms: | 1-(3-methoxyphenyl)-N-[5-[2-(4-methoxyphenyl)-2-oxidanylidene-ethyl]sulfanyl-1,3,4-thiadiazol-2-yl]-5-oxidanylidene-pyrrolidine-3-carboxamide | 1-(3-methoxyphenyl)-N-[5-[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]-5-oxopyrrolidine-3-carboxamide | 1-(3-methoxyphenyl)-N-[5-[[2-(4-methoxyphenyl)-2-oxoethyl]thio]-1,3,4-thiadiazol-2-yl]-5-oxo-3-pyrrolidinecarboxamide | 5-keto-N-[5-[[2-keto-2-(4-methoxyphenyl)ethyl]thio]-1,3,4-thiadiazol-2-yl]-1-(3-methoxyphenyl)pyrrolidine-3-carboxamide | MLS000724886 | SMR000237075 | cid_15944862 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N4O5S2 |
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| Mol. Mass. | 498.575 |
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| SMILES | COc1ccc(cc1)C(=O)CSc1nnc(NC(=O)C2CN(C(=O)C2)c2cccc(OC)c2)s1 |
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| Structure | 
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