Ki Summary

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Target

Epstein-Barr nuclear antigen 1

Ligand

BDBM62483

Substrate/Competitor

n/a

Meas. Tech.

Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1)

IC50

5559±n/a nM

Citation

PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the Epstein-Barr virus nuclear antigen 1 (EBNA-1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Epstein-Barr nuclear antigen 1

Name:

Epstein-Barr nuclear antigen 1

Synonyms:

EBNA-1 protein | EBNA1 | EBNA1_EBVB9 | Epstein-Barr virus protease (EBV Pr)

Type:

Enzyme Catalytic Domain

Mol. Mass.:

56444.81

Organism:

Human herpesvirus 4

Description:

gi_23893623

Residue:

641

Sequence:

MSDEGPGTGPGNGLGEKGDTSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGS
GSGPRHRDGVRRPQKRPSCIGCKGTHGGTGAGAGAGGAGAGGAGAGGGAGAGGGAGGAGG
AGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGG
AGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGA
GAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGGAGAGGGAGGAGAGGAGGAGAGGA
GGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRER
ARGGSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGEADYFEYHQE
GGPDGEPDVPPGAIEQGPADDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFEN
IAEGLRALLARSHVERTTDEGTWVAGVFVYGGSKTSLYNLRRGTALAIPQCRLTPLSRLP
FGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIRVTVCSF
DDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE

BDBM62483

n/a

Name

BDBM62483

Synonyms:

2-[(4-naphthalen-2-ylsulfonylpiperazin-1-yl)methyl]-1H-quinazolin-4-one | 2-[[4-(2-naphthalenylsulfonyl)-1-piperazinyl]methyl]-1H-quinazolin-4-one | 2-[[4-(2-naphthylsulfonyl)piperazino]methyl]-1H-quinazolin-4-one | MLS000761027 | SMR000372327 | cid_4879718

Type

Small organic molecule

Emp. Form.

C23H22N4O3S

Mol. Mass.

434.511

SMILES

O=c1[nH]c(CN2CCN(CC2)S(=O)(=O)c2ccc3ccccc3c2)nc2ccccc12

Structure