Ki Summary

Reaction Details

Report a problem with these data

Target

Heat shock factor protein 1

Ligand

BDBM37899

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1)

EC50

>195000±0 nM

Citation

PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM37899

n/a

Name

BDBM37899

Synonyms:

MLS000086255 | N-(1,3-benzodioxol-5-yl)-2-(1-keto-3-methyl-2-isoquinolyl)acetamide | N-(1,3-benzodioxol-5-yl)-2-(3-methyl-1-oxidanylidene-isoquinolin-2-yl)ethanamide | N-(1,3-benzodioxol-5-yl)-2-(3-methyl-1-oxo-2-isoquinolinyl)acetamide | N-(1,3-benzodioxol-5-yl)-2-(3-methyl-1-oxoisoquinolin-2-yl)acetamide | N-1,3-benzodioxol-5-yl-2-(3-methyl-1-oxoisoquinolin-2(1H)-yl)acetamide | SMR000021764 | cid_3236683

Type

Small organic molecule

Emp. Form.

C19H16N2O4

Mol. Mass.

336.3413

SMILES

Cc1cc2ccccc2c(=O)n1CC(=O)Nc1ccc2OCOc2c1

Structure