| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Heat shock factor protein 1 |
|---|
| Ligand | BDBM62839 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) |
|---|
| EC50 | >195000±0 nM |
|---|
| Citation |  PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Heat shock factor protein 1 |
|---|
| Name: | Heat shock factor protein 1 |
|---|
| Synonyms: | HSF1_MOUSE | Hsf1 | Hsf1 protein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 57208.68 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | P38532 |
|---|
| Residue: | 525 |
|---|
| Sequence: | MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
|
|
|
|---|
| BDBM62839 |
|---|
| n/a |
|---|
| Name | BDBM62839 |
|---|
| Synonyms: | 5,5-dimethyl-2,6-dihydro-[1,2,4]triazol[3,4-a]isoquinoline-3-thione | 5,5-dimethyl-2,6-dihydro-[1,2,4]triazolo[3,4-a]isoquinoline-3-thione | MLS000107006 | SMR000111380 | US10864248, Compound 3 | cid_870599 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H13N3S |
|---|
| Mol. Mass. | 231.317 |
|---|
| SMILES | CC1(C)Cc2ccccc2-c2n[nH]c(=S)n12 |
|---|
| Structure | 
|
|---|
Search and Browse
