| Reaction Details |
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 | Report a problem with these data |
| Target | Heat shock factor protein 1 |
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| Ligand | BDBM39069 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) |
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| EC50 | 4616±1065 nM |
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| Citation |  PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Heat shock factor protein 1 |
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| Name: | Heat shock factor protein 1 |
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| Synonyms: | HSF1_MOUSE | Hsf1 | Hsf1 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57208.68 |
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| Organism: | Mus musculus |
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| Description: | P38532 |
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| Residue: | 525 |
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| Sequence: | MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
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| BDBM39069 |
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| n/a |
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| Name | BDBM39069 |
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| Synonyms: | (Z)-3-(1,3-benzodioxol-5-ylamino)-1-(2-pyridinyl)-2-propen-1-one | (Z)-3-(1,3-benzodioxol-5-ylamino)-1-(2-pyridyl)prop-2-en-1-one | (Z)-3-(1,3-benzodioxol-5-ylamino)-1-pyridin-2-yl-prop-2-en-1-one | (Z)-3-(1,3-benzodioxol-5-ylamino)-1-pyridin-2-ylprop-2-en-1-one | MLS000108346 | SMR000104305 | cid_5310753 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N2O3 |
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| Mol. Mass. | 268.2674 |
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| SMILES | O=C(CC=Nc1ccc2OCOc2c1)c1ccccn1 |w:4.4| |
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| Structure | 
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