Ki Summary

Reaction Details

Report a problem with these data

Target

Heat shock factor protein 1

Ligand

BDBM63374

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1)

EC50

>195000±0 nM

Citation

PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM63374

n/a

Name

BDBM63374

Synonyms:

MLS000123651 | N-(4-Cyclopropylsulfamoyl-phenyl)-2-(4-methyl-piperidin-1-yl)-acetamide | N-[4-(cyclopropylsulfamoyl)phenyl]-2-(4-methyl-1-piperidinyl)acetamide;oxalic acid | N-[4-(cyclopropylsulfamoyl)phenyl]-2-(4-methylpiperidin-1-yl)acetamide;oxalic acid | N-[4-(cyclopropylsulfamoyl)phenyl]-2-(4-methylpiperidin-1-yl)ethanamide;ethanedioic acid | N-[4-(cyclopropylsulfamoyl)phenyl]-2-(4-methylpiperidino)acetamide;oxalic acid | SMR000124224 | cid_16187052

Type

Small organic molecule

Emp. Form.

C17H25N3O3S

Mol. Mass.

351.464

SMILES

CC1CCN(CC(=O)Nc2ccc(cc2)S(=O)(=O)NC2CC2)CC1

Structure