| Reaction Details |
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 | Report a problem with these data |
| Target | Heat shock factor protein 1 |
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| Ligand | BDBM43491 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) |
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| EC50 | >195000±0 nM |
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| Citation |  PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Heat shock factor protein 1 |
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| Name: | Heat shock factor protein 1 |
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| Synonyms: | HSF1_MOUSE | Hsf1 | Hsf1 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57208.68 |
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| Organism: | Mus musculus |
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| Description: | P38532 |
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| Residue: | 525 |
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| Sequence: | MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
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| BDBM43491 |
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| n/a |
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| Name | BDBM43491 |
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| Synonyms: | (3E,5E)-3,5-bis(3,4,5-trimethoxybenzylidene)tetrahydropyran-4-one | (3E,5E)-3,5-bis[(3,4,5-trimethoxyphenyl)methylidene]-4-oxanone | (3E,5E)-3,5-bis[(3,4,5-trimethoxyphenyl)methylidene]oxan-4-one | 3,5-di(3,4,5-trimethoxybenzylidene)tetrahydro-2H-pyran-4-one | MLS000860258 | SMR000461037 | cid_5703458 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H28O8 |
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| Mol. Mass. | 456.485 |
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| SMILES | COc1cc(\C=C2/COC\C(=C/c3cc(OC)c(OC)c(OC)c3)C2=O)cc(OC)c1OC |
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| Structure | 
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