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TargetHeat shock factor protein 1
LigandBDBM64129
Substrate/Competitorn/a
Meas. Tech.Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1)
EC50>195000±0 nM
Citation PubChem, PC Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Heat shock factor protein 1
Name:Heat shock factor protein 1
Synonyms:HSF1_MOUSE | Hsf1 | Hsf1 protein
Type:Enzyme Catalytic Domain
Mol. Mass.:57208.68
Organism:Mus musculus
Description:P38532
Residue:525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
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  Blast E-value cutoff:
BDBM64129
n/a
NameBDBM64129
Synonyms:MLS001202278 | N-(2-ethylphenyl)-3-(4-methoxyphenyl)sulfonyl-propanamide | N-(2-ethylphenyl)-3-(4-methoxyphenyl)sulfonyl-propionamide | N-(2-ethylphenyl)-3-(4-methoxyphenyl)sulfonylpropanamide | N-(2-ethylphenyl)-3-[(4-methoxyphenyl)sulfonyl]propanamide | SMR000564981 | cid_5072004
TypeSmall organic molecule
Emp. Form.C18H21NO4S
Mol. Mass.347.429
SMILESCCc1ccccc1NC(=O)CCS(=O)(=O)c1ccc(OC)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: