| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase |
|---|
| Ligand | BDBM34358 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin |
|---|
| EC50 | 180000±n/a nM |
|---|
| Citation |  PubChem, PC Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Serine/threonine-protein phosphatase |
|---|
| Name: | Serine/threonine-protein phosphatase |
|---|
| Synonyms: | calcineurin A1, putative | calmodulin-binding protein 1, putative | serine/threonine-protein phosphatase 2B catalytic subunit A1, putative |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 69558.03 |
|---|
| Organism: | Candida dubliniensis CD36 |
|---|
| Description: | gi_223640082 |
|---|
| Residue: | 607 |
|---|
| Sequence: | MSGNTVQRNTEQINNALNAIQHRRTTTGNDLNHTNQRIISQNSINDKDYTIYITDDGEKY
STVERAVKSVDPPVTFKPKDEQVFLSNGKPNHQFLKQHFIHEGRLHEHQAIQILKQATHL
LSKESNLLNVPAPVTICGDVHGQYYDLMKLFEVGGDPATTKYLFLGDYVDRGSFSIECLL
YLYSLKINYPDTFWMLRGNHECRHLTEYFTFKNECLHKYSEQLYEECLVSFNALPLAAIM
NEQFFCVHGGLSPQLTSLDSLRKLHRFREPPTKGLMCDLLWADPIEEYDEDNIDQEYVTN
VVRGCSFAFTYKAACKFLDKTKLLSVIRAHEAQNAGYRMYKRTKTMGFPSLLTMFSAPNY
LDSYNNKAAVLKYENNVMNIRQFNASPHPYWLPHFMDVFTWSLPFVGEKVTDMLVSILNV
CTEEELDEDLPFSESEIGVATKTTKTTTPVSPVSPKAHPPSTRITSPYKSTKLVESDNNP
NTNNDDSEMTLEEKKQALRNKIIAIGKMSRMFQVLREEQENVAHLKELNRGSLPKGSLLH
GVDGLKNTINSFEEAKAADRINEALPPSPEDIQRLKQEKNTRIRQQIENQEMSGPVFQRL
IRRLSQS
|
|
|
|---|
| BDBM34358 |
|---|
| n/a |
|---|
| Name | BDBM34358 |
|---|
| Synonyms: | 4-[benzyl(ethyl)sulfamoyl]-N-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide | 4-[ethyl-(phenylmethyl)sulfamoyl]-N-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide | 4-{[benzyl(ethyl)amino]sulfonyl}-N-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide | MLS000086333 | SMR000021835 | cid_2158923 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H24N4O5S |
|---|
| Mol. Mass. | 492.547 |
|---|
| SMILES | CCN(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)C(=O)Nc1nnc(o1)-c1ccccc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
