| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase |
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| Ligand | BDBM64548 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin |
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| EC50 | 180000±n/a nM |
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| Citation |  PubChem, PC Luminesence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Serine/threonine-protein phosphatase |
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| Name: | Serine/threonine-protein phosphatase |
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| Synonyms: | calcineurin A1, putative | calmodulin-binding protein 1, putative | serine/threonine-protein phosphatase 2B catalytic subunit A1, putative |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 69558.03 |
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| Organism: | Candida dubliniensis CD36 |
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| Description: | gi_223640082 |
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| Residue: | 607 |
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| Sequence: | MSGNTVQRNTEQINNALNAIQHRRTTTGNDLNHTNQRIISQNSINDKDYTIYITDDGEKY
STVERAVKSVDPPVTFKPKDEQVFLSNGKPNHQFLKQHFIHEGRLHEHQAIQILKQATHL
LSKESNLLNVPAPVTICGDVHGQYYDLMKLFEVGGDPATTKYLFLGDYVDRGSFSIECLL
YLYSLKINYPDTFWMLRGNHECRHLTEYFTFKNECLHKYSEQLYEECLVSFNALPLAAIM
NEQFFCVHGGLSPQLTSLDSLRKLHRFREPPTKGLMCDLLWADPIEEYDEDNIDQEYVTN
VVRGCSFAFTYKAACKFLDKTKLLSVIRAHEAQNAGYRMYKRTKTMGFPSLLTMFSAPNY
LDSYNNKAAVLKYENNVMNIRQFNASPHPYWLPHFMDVFTWSLPFVGEKVTDMLVSILNV
CTEEELDEDLPFSESEIGVATKTTKTTTPVSPVSPKAHPPSTRITSPYKSTKLVESDNNP
NTNNDDSEMTLEEKKQALRNKIIAIGKMSRMFQVLREEQENVAHLKELNRGSLPKGSLLH
GVDGLKNTINSFEEAKAADRINEALPPSPEDIQRLKQEKNTRIRQQIENQEMSGPVFQRL
IRRLSQS
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| BDBM64548 |
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| n/a |
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| Name | BDBM64548 |
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| Synonyms: | MLS000087310 | N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-5-methylisoxazole-3-carboxamide | N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-1,2-oxazole-3-carboxamide | N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-3-isoxazolecarboxamide | N-(3-cyano-4,5,6,7-tetrahydrobenzothiophen-2-yl)-5-methyl-isoxazole-3-carboxamide | SMR000023533 | cid_3239681 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13N3O2S |
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| Mol. Mass. | 287.337 |
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| SMILES | Cc1cc(no1)C(=O)Nc1sc2CCCCc2c1C#N |
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| Structure | 
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