| Reaction Details |
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 | Report a problem with these data |
| Target | ATP-dependent molecular chaperone HSP82 |
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| Ligand | BDBM64893 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole |
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| EC50 | >160000±0 nM |
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| Citation |  PubChem, PC Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| ATP-dependent molecular chaperone HSP82 |
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| Name: | ATP-dependent molecular chaperone HSP82 |
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| Synonyms: | heat shock protein 90 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 80784.12 |
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| Organism: | Candida albicans |
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| Description: | gi_994798 |
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| Residue: | 707 |
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| Sequence: | MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLE
SEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMI
GQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFL
KEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLE
EVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDP
LAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLS
FIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSK
NIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVE
KSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKE
IKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTM
SSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSN
FAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
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| BDBM64893 |
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| n/a |
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| Name | BDBM64893 |
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| Synonyms: | 2-(4-Chloro-phenoxy)-N-(2-oxo-tetrahydro-thiophen-3-yl)-acetamide | 2-(4-chloranylphenoxy)-N-(2-oxidanylidenethiolan-3-yl)ethanamide | 2-(4-chlorophenoxy)-N-(2-ketotetrahydrothiophen-3-yl)acetamide | 2-(4-chlorophenoxy)-N-(2-oxo-3-thiolanyl)acetamide | 2-(4-chlorophenoxy)-N-(2-oxothiolan-3-yl)acetamide | MLS000071973 | SMR000012446 | cid_654685 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12ClNO3S |
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| Mol. Mass. | 285.747 |
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| SMILES | Clc1ccc(OCC(=O)NC2CCSC2=O)cc1 |
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| Structure | 
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