| Reaction Details |
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 | Report a problem with these data |
| Target | ATP-dependent molecular chaperone HSP82 |
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| Ligand | BDBM64541 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole |
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| EC50 | 896±1160 nM |
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| Citation |  PubChem, PC Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| ATP-dependent molecular chaperone HSP82 |
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| Name: | ATP-dependent molecular chaperone HSP82 |
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| Synonyms: | heat shock protein 90 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 80784.12 |
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| Organism: | Candida albicans |
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| Description: | gi_994798 |
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| Residue: | 707 |
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| Sequence: | MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLE
SEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMI
GQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFL
KEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLE
EVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDP
LAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLS
FIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSK
NIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVE
KSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKE
IKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTM
SSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSN
FAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
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| BDBM64541 |
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| n/a |
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| Name | BDBM64541 |
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| Synonyms: | 1-[2-(dimethylamino)ethylamino]-3-methyl-2-prop-2-enyl-4-pyrido[1,2-a]benzimidazolecarbonitrile | 1-[2-(dimethylamino)ethylamino]-3-methyl-2-prop-2-enyl-pyrido[1,2-a]benzimidazole-4-carbonitrile | 1-[2-(dimethylamino)ethylamino]-3-methyl-2-prop-2-enylpyrido[1,2-a]benzimidazole-4-carbonitrile | 2-allyl-1-[2-(dimethylamino)ethylamino]-3-methyl-pyrido[1,2-a]benzimidazole-4-carbonitrile | MLS000081312 | SMR000045230 | cid_664345 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N5 |
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| Mol. Mass. | 333.4301 |
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| SMILES | CN(C)CCNc1c(CC=C)c(C)c(C#N)c2nc3ccccc3n12 |
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| Structure | 
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