| Reaction Details |
|---|
 | Report a problem with these data |
| Target | ATP-dependent molecular chaperone HSP82 |
|---|
| Ligand | BDBM34278 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole |
|---|
| EC50 | >160000±0 nM |
|---|
| Citation |  PubChem, PC Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| ATP-dependent molecular chaperone HSP82 |
|---|
| Name: | ATP-dependent molecular chaperone HSP82 |
|---|
| Synonyms: | heat shock protein 90 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 80784.12 |
|---|
| Organism: | Candida albicans |
|---|
| Description: | gi_994798 |
|---|
| Residue: | 707 |
|---|
| Sequence: | MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLE
SEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMI
GQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFL
KEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLE
EVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDP
LAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLS
FIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSK
NIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVE
KSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKE
IKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTM
SSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSN
FAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
|
|
|
|---|
| BDBM34278 |
|---|
| n/a |
|---|
| Name | BDBM34278 |
|---|
| Synonyms: | 1-(3,4-dihydroxyphenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone | 1-(3,4-dihydroxyphenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]thio]ethanone | 1-[3,4-bis(oxidanyl)phenyl]-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone | MLS000080517 | SMR000038049 | cid_665183 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H19N3O4S |
|---|
| Mol. Mass. | 385.437 |
|---|
| SMILES | CCn1c(SCC(=O)c2ccc(O)c(O)c2)nnc1-c1ccccc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
