| Reaction Details |
|---|
 | Report a problem with these data |
| Target | ATP-dependent molecular chaperone HSP82 |
|---|
| Ligand | BDBM64922 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole |
|---|
| EC50 | 866±1291 nM |
|---|
| Citation |  PubChem, PC Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| ATP-dependent molecular chaperone HSP82 |
|---|
| Name: | ATP-dependent molecular chaperone HSP82 |
|---|
| Synonyms: | heat shock protein 90 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 80784.12 |
|---|
| Organism: | Candida albicans |
|---|
| Description: | gi_994798 |
|---|
| Residue: | 707 |
|---|
| Sequence: | MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLE
SEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMI
GQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFL
KEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLE
EVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDP
LAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLS
FIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSK
NIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVE
KSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKE
IKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTM
SSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSN
FAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
|
|
|
|---|
| BDBM64922 |
|---|
| n/a |
|---|
| Name | BDBM64922 |
|---|
| Synonyms: | 3-methyl-2-thiophenecarboxylic acid [2-[(3-carbamoyl-2-thiophenyl)amino]-2-oxoethyl] ester | 3-methylthiophene-2-carboxylic acid [2-[(3-carbamoyl-2-thienyl)amino]-2-keto-ethyl] ester | MLS000098628 | SMR000068639 | [2-[(3-aminocarbonylthiophen-2-yl)amino]-2-oxidanylidene-ethyl] 3-methylthiophene-2-carboxylate | [2-[(3-carbamoylthiophen-2-yl)amino]-2-oxoethyl] 3-methylthiophene-2-carboxylate | cid_2568311 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H12N2O4S2 |
|---|
| Mol. Mass. | 324.375 |
|---|
| SMILES | Cc1ccsc1C(=O)OCC(=O)Nc1sccc1C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
