| Reaction Details |
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 | Report a problem with these data |
| Target | ATP-dependent molecular chaperone HSP82 |
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| Ligand | BDBM64923 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole |
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| EC50 | 421±2671 nM |
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| Citation |  PubChem, PC Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| ATP-dependent molecular chaperone HSP82 |
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| Name: | ATP-dependent molecular chaperone HSP82 |
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| Synonyms: | heat shock protein 90 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 80784.12 |
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| Organism: | Candida albicans |
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| Description: | gi_994798 |
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| Residue: | 707 |
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| Sequence: | MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLE
SEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMI
GQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFL
KEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLE
EVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDP
LAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLS
FIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSK
NIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVE
KSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKE
IKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTM
SSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSN
FAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
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| BDBM64923 |
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| n/a |
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| Name | BDBM64923 |
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| Synonyms: | MLS000056555 | N-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]-3,5-dimethyl-1-phenyl-4-pyrazolecarboxamide | N-[5-(2-furyl)-1,3,4-oxadiazol-2-yl]-3,5-dimethyl-1-phenyl-pyrazole-4-carboxamide | N-[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]-3,5-dimethyl-1-phenyl-pyrazole-4-carboxamide | N-[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]-3,5-dimethyl-1-phenylpyrazole-4-carboxamide | SMR000064662 | cid_2533856 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15N5O3 |
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| Mol. Mass. | 349.3434 |
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| SMILES | Cc1nn(c(C)c1C(=O)Nc1nnc(o1)-c1ccco1)-c1ccccc1 |
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| Structure | 
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