| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily KQT member 2 |
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| Ligand | BDBM64871 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Mode of action - deactivation constant concentration response for ztz240, a potentiator of KCNQ2 potassium channels |
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| EC50 | 5900±n/a nM |
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| Citation |  PubChem, PC Mode of action - deactivation constant concentration response for ztz240, a potentiator of KCNQ2 potassium channels PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Potassium voltage-gated channel subfamily KQT member 2 |
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| Name: | Potassium voltage-gated channel subfamily KQT member 2 |
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| Synonyms: | KCNQ2_RAT | Kcnq2 | Voltage-gated potassium channel subunit Kv7.2 | potassium voltage-gated channel, KQT-like subfamily, member 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 93984.01 |
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| Organism: | Rattus norvegicus |
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| Description: | EBI_100117 |
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| Residue: | 852 |
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| Sequence: | MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTG
GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
QYYERTVTVPMISSQTQTYGASRLIPPLNQLEMLRNLKSKSGLTFRKEPQPEPSPSQKVS
LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRARQAFRI
KGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKE
SLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPTITDKDRTKGPAETELPEDP
SMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSR
DHADKHGCIIKIVRSTSSTGQRKYAAPPVMPPAECPPSTSWQQSHQRHGTSPVGDHGSLV
RIPPPPAHERSLSAYSGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELER
SFSGFSISQSKENLNALASCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEG
PFGDVAWAGPRK
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| BDBM64871 |
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| n/a |
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| Name | BDBM64871 |
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| Synonyms: | N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide | N-(6-chloro-3-pyridinyl)-4-fluorobenzamide | N-(6-chloro-3-pyridyl)-4-fluoro-benzamide | N-(6-chloropyridin-3-yl)-4-fluorobenzamide | US11365181, Compound ZTZ240 | ZTZ240 | cid_3780776 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8ClFN2O |
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| Mol. Mass. | 250.656 |
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| SMILES | Fc1ccc(cc1)C(=O)Nc1ccc(Cl)nc1 |
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| Structure | 
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