Ki Summary

Reaction Details

Report a problem with these data

Target

G-protein coupled receptor 35

Ligand

BDBM41203

Substrate/Competitor

n/a

Meas. Tech.

SAR analysis of compounds that inhibit NOD1 - Set 2

IC50

1630±n/a nM

Citation

PubChem, PC SAR analysis of compounds that inhibit NOD1 - Set 2 PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

G-protein coupled receptor 35

Name:

G-protein coupled receptor 35

Synonyms:

G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN

Type:

Enzyme Catalytic Domain

Mol. Mass.:

34085.57

Organism:

Homo sapiens (Human)

Description:

gi_33695097

Residue:

309

Sequence:

MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMT
NLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRH
PLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGF
YLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVR
LAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKS
QDSLCVTLA

BDBM41203

n/a

Name

BDBM41203

Synonyms:

2-(1,3-Dimethyl-2,6-dioxo-7-propyl-2,3,6,7-tetrahydro-1H-purin-8-ylsulfanyl)-N-(4,5,6,7-tetrahydro-benzothiazol-2-yl)-acetamide | 2-(1,3-dimethyl-2,6-dioxo-7-propylpurin-8-yl)sulfanyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide | 2-[(1,3-dimethyl-2,6-dioxo-7-propyl-8-purinyl)thio]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide | 2-[(2,6-diketo-1,3-dimethyl-7-propyl-purin-8-yl)thio]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide | 2-[1,3-dimethyl-2,6-bis(oxidanylidene)-7-propyl-purin-8-yl]sulfanyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)ethanamide | MLS000029447 | SMR000002300 | cid_653676

Type

Small organic molecule

Emp. Form.

C19H24N6O3S2

Mol. Mass.

448.562

SMILES

CCCn1c(SCC(=O)Nc2nc3CCCCc3s2)nc2n(C)c(=O)n(C)c(=O)c12

Structure