| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-6-phosphate 1-dehydrogenase |
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| Ligand | BDBM61930 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | G6DPH counterscreen for TbHK1 inhibitors - Analogues series |
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| IC50 | >25000±n/a nM |
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| Citation |  PubChem, PC G6DPH counterscreen for TbHK1 inhibitors - Analogues series PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Glucose-6-phosphate 1-dehydrogenase |
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| Name: | Glucose-6-phosphate 1-dehydrogenase |
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| Synonyms: | G6PD_LEUME | glucose-6-phosphate dehydrogenase | zwf |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 54421.26 |
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| Organism: | Leuconostoc mesenteroides |
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| Description: | gi_149631 |
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| Residue: | 486 |
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| Sequence: | MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVR
DSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVA
PRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHY
LGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQN
HTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKP
YLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFG
SEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMI
HDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGD
AWVFKG
|
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|
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| BDBM61930 |
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| n/a |
|---|
| Name | BDBM61930 |
|---|
| Synonyms: | 3-keto-2-phenyl-1,2-benzothiazole-6-carbonitrile | 3-oxidanylidene-2-phenyl-1,2-benzothiazole-6-carbonitrile | 3-oxo-2-phenyl-1,2-benzothiazole-6-carbonitrile | KSC-6-118 | KUC104129N | cid_44602378 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H8N2OS |
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| Mol. Mass. | 252.291 |
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| SMILES | O=c1n(sc2cc(ccc12)C#N)-c1ccccc1 |
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| Structure | 
|
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