| Reaction Details |
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 | Report a problem with these data |
| Target | Inward rectifier potassium channel 2 |
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| Ligand | BDBM65864 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 |
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| IC50 | 54213±38096 nM |
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| Citation |  PubChem, PC Confirmation dose response assay for compounds that inhibit/block inward-rectifying potassium ion channel Kir2.1 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Inward rectifier potassium channel 2 |
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| Name: | Inward rectifier potassium channel 2 |
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| Synonyms: | Irk1 | KCNJ2_MOUSE | Kcnj2 | inward rectifier potassium channel 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48383.35 |
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| Organism: | Mus musculus |
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| Description: | gi_6680530 |
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| Residue: | 428 |
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| Sequence: | MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFIN
VGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDTSKVSK
ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVM
AKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEG
EYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEG
MVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARD
LAEKKYILSNANSFCYENEVALTSKEEEEDSENGVPESTSTDSPPGIDLHNQASVPLEPR
PLRRESEI
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| BDBM65864 |
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| n/a |
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| Name | BDBM65864 |
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| Synonyms: | 1-adamantyl-(1-propyl-4-piperidyl)amine | MLS000974665 | N-(1-adamantyl)-1-propyl-4-piperidinamine | N-(1-adamantyl)-1-propyl-piperidin-4-amine | N-(1-adamantyl)-1-propylpiperidin-4-amine | N-1-adamantyl-1-propyl-4-piperidinamine | SMR000496476 | cid_2846583 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H32N2 |
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| Mol. Mass. | 276.4601 |
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| SMILES | [H]C12CC3([H])CC([H])(C1)CC(C2)(C3)NC1CCN(CCC)CC1 |TLB:8:1:12:6.9.5,8:6:12:1.11.2,THB:2:1:9:3.12.5| |
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| Structure | 
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