| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily KQT member 2 |
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| Ligand | BDBM65890 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Mode of action assay-Automated electrophysiology assay of compounds that potentiate KCNQ2 potassium channel |
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| EC50 | 3020±810 nM |
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| Citation |  PubChem, PC Mode of action assay-Automated electrophysiology assay of compounds that potentiate KCNQ2 potassium channel PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Potassium voltage-gated channel subfamily KQT member 2 |
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| Name: | Potassium voltage-gated channel subfamily KQT member 2 |
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| Synonyms: | KCNQ2_RAT | Kcnq2 | Voltage-gated potassium channel subunit Kv7.2 | potassium voltage-gated channel, KQT-like subfamily, member 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 93984.01 |
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| Organism: | Rattus norvegicus |
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| Description: | EBI_100117 |
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| Residue: | 852 |
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| Sequence: | MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTG
GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
QYYERTVTVPMISSQTQTYGASRLIPPLNQLEMLRNLKSKSGLTFRKEPQPEPSPSQKVS
LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRARQAFRI
KGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKE
SLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPTITDKDRTKGPAETELPEDP
SMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSR
DHADKHGCIIKIVRSTSSTGQRKYAAPPVMPPAECPPSTSWQQSHQRHGTSPVGDHGSLV
RIPPPPAHERSLSAYSGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELER
SFSGFSISQSKENLNALASCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEG
PFGDVAWAGPRK
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| BDBM65890 |
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| n/a |
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| Name | BDBM65890 |
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| Synonyms: | 5-chloranyl-2-[(4-methylphenyl)methylsulfonyl]-N-(5-propyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide | 5-chloro-2-(4-methylbenzyl)sulfonyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide | 5-chloro-2-[(4-methylphenyl)methylsulfonyl]-N-(5-propyl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamide | 5-chloro-2-[(4-methylphenyl)methylsulfonyl]-N-(5-propyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide | MLS001116147 | SMR000625779 | cid_16014339 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18ClN5O3S2 |
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| Mol. Mass. | 451.95 |
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| SMILES | CCCc1nnc(NC(=O)c2nc(ncc2Cl)S(=O)(=O)Cc2ccc(C)cc2)s1 |
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| Structure | 
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