| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily KQT member 2 |
|---|
| Ligand | BDBM65943 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel |
|---|
| EC50 | 6310±4970 nM |
|---|
| Citation |  PubChem, PC Dose response of Retigabine-insensitive compounds that potentiate KCNQ2 potassium channel PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Potassium voltage-gated channel subfamily KQT member 2 |
|---|
| Name: | Potassium voltage-gated channel subfamily KQT member 2 |
|---|
| Synonyms: | KCNQ2_RAT | Kcnq2 | Voltage-gated potassium channel subunit Kv7.2 | potassium voltage-gated channel, KQT-like subfamily, member 2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 93984.01 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | EBI_100117 |
|---|
| Residue: | 852 |
|---|
| Sequence: | MVQKSRNGGVYPGTSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSVLSKPRTG
GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
QYYERTVTVPMISSQTQTYGASRLIPPLNQLEMLRNLKSKSGLTFRKEPQPEPSPSQKVS
LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLDDSPSKVPKSWSFGDRSRARQAFRI
KGAASRQNSEEASLPGEDIVEDNKSCNCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKE
SLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPTITDKDRTKGPAETELPEDP
SMMGRLGKVEKQVLSMEKKLDFLVSIYTQRMGIPPAETEAYFGAKEPEPAPPYHSPEDSR
DHADKHGCIIKIVRSTSSTGQRKYAAPPVMPPAECPPSTSWQQSHQRHGTSPVGDHGSLV
RIPPPPAHERSLSAYSGGNRASTEFLRLEGTPACRPSEAALRDSDTSISIPSVDHEELER
SFSGFSISQSKENLNALASCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEG
PFGDVAWAGPRK
|
|
|
|---|
| BDBM65943 |
|---|
| n/a |
|---|
| Name | BDBM65943 |
|---|
| Synonyms: | 1-(2,4-dichlorobenzyl)-3-(6-fluoro-3-pyridyl)urea | 1-[(2,4-dichlorophenyl)methyl]-3-(6-fluoranylpyridin-3-yl)urea | 1-[(2,4-dichlorophenyl)methyl]-3-(6-fluoro-3-pyridinyl)urea | 1-[(2,4-dichlorophenyl)methyl]-3-(6-fluoropyridin-3-yl)urea | VU0417927-1 | cid_45489560 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H10Cl2FN3O |
|---|
| Mol. Mass. | 314.142 |
|---|
| SMILES | Fc1ccc(NC(=O)NCc2ccc(Cl)cc2Cl)cn1 |
|---|
| Structure | 
|
|---|
Search and Browse
